David M Liberati Selected Research

Wounds and Injuries (Trauma)

1/2022	The effect of tranexamic acid dosing regimen on trauma/hemorrhagic shock-related glycocalyx degradation and endothelial barrier permeability: An in vitro model.
1/2021	The protective role of estrogen on endothelial and glycocalyx barriers after shock conditions: A microfluidic study.
11/2019	Protective effects of plasma products on the endothelial-glycocalyx barrier following trauma-hemorrhagic shock: Is sphingosine-1 phosphate responsible?
1/2019	Red blood cell storage and adhesion to vascular endothelium under normal or stress conditions: An in vitro microfluidic study.
1/2018	Microfluidics: A high-throughput system for the assessment of the endotheliopathy of trauma and the effect of timing of plasma administration on ameliorating shock-associated endothelial dysfunction.
12/2017	Disparate effects of catecholamines under stress conditions on endothelial glycocalyx injury: An in vitro model.
3/2017	Tranexamic acid and the gut barrier: Protection by inhibition of trypsin uptake and activation of downstream intestinal proteases.
1/2017	Early tranexamic acid administration ameliorates the endotheliopathy of trauma and shock in an in vitro model.
12/2015	Early tranexamic acid administration: A protective effect on gut barrier function following ischemia/reperfusion injury.
1/2015	Estrogen modulates intestinal mucus physiochemical properties and protects against oxidant injury.

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David M Liberati Research Topics

Disease

16	Shock 01/2022 - 05/2005
14	Wounds and Injuries (Trauma) 01/2022 - 05/2008
13	Hypoxia (Hypoxemia) 01/2022 - 08/2003
10	Hemorrhagic Shock 01/2022 - 10/2008
8	Pneumonia (Pneumonitis) 04/2012 - 10/2004
6	Infections 09/2014 - 10/2004
3	Critical Illness (Critically Ill) 01/2018 - 03/2003
3	Necrosis 09/2014 - 08/2009
2	Hemorrhage 01/2021 - 01/2015
2	Obesity 01/2020 - 12/2016
2	Sepsis (Septicemia) 01/2019 - 06/2008
2	Ulcerative Colitis 10/2014 - 09/2014
2	Lung Injury 10/2013 - 08/2009
2	Ischemia 10/2013 - 10/2003
2	Healthcare-Associated Pneumonia 04/2010 - 05/2009
1	Hyperglycemia 11/2018
1	Hypernatremia 01/2018
1	Reperfusion Injury 12/2015
1	Bacterial Pneumonia 04/2010
1	Inflammation (Inflammations) 06/2009
1	Hypersensitivity (Allergy) 06/2008

Drug/Important Bio-Agent (IBA)

10	Epinephrine (Adrenaline)FDA LinkGeneric 01/2022 - 12/2016
8	Secretory Immunoglobulin A (SIgA)IBA 09/2014 - 10/2003
7	Immunoglobulin A (IgA)IBA 09/2014 - 03/2003
4	Tranexamic Acid (AMCA)FDA Link 01/2022 - 12/2015
4	CytokinesIBA 12/2016 - 07/2007
4	Ethanol (Ethyl Alcohol)IBA 12/2009 - 10/2007
3	Estrogens (Estrogen)FDA Link 01/2021 - 09/2011
3	Virulence Factors (Pathogenicity Factors)IBA 04/2013 - 10/2004
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2021 - 12/2017
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 11/2018
2	TrypsinIBA 03/2017 - 12/2015
2	Peptide Hydrolases (Proteases)FDA Link 03/2017 - 10/2004
2	EnzymesIBA 03/2017 - 12/2015
2	Phosphatidylcholines (Phosphatidylcholine)IBA 10/2014 - 09/2014
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2014 - 05/2005
2	Propidium (Propidium Iodide)IBA 04/2013 - 08/2009
2	salicylhydroxamic acid (SHAM)IBA 06/2009 - 10/2008
2	IgA-specific serine endopeptidaseIBA 05/2009 - 10/2004
2	Immunoglobulin G (IgG)IBA 03/2006 - 11/2005
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2022
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2022
1	Testosterone (Sustanon)FDA Link 01/2021
1	Phosphates (Orthophosphate)IBA 11/2019
1	Syndecan-1 (Syndecan 1)IBA 11/2019
1	Hyaluronic Acid (Hyaluronan)IBA 11/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2018
1	SodiumIBA 01/2018
1	Crystalloid SolutionsIBA 01/2018
1	SolutionsIBA 01/2018
1	HEPESIBA 01/2018
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 12/2017
1	AdipokinesIBA 12/2016
1	Gonadal Steroid Hormones (Sex Hormones)IBA 12/2016
1	Phenobarbital (Luminal)FDA Link 12/2015
1	Oxidants (Oxidizing Agents)IBA 01/2015
1	Interleukin-6 (Interleukin 6)IBA 09/2014
1	Verapamil (Calan)FDA LinkGeneric 07/2014
1	Nicotine FDA Link 10/2013
1	fluorescein isothiocyanate dextranIBA 04/2013
1	ProteomeIBA 07/2012
1	Dihydrotestosterone (Androstanolone)IBA 04/2012
1	Estradiol (Delestrogen)FDA LinkGeneric 04/2012
1	Cimetidine (Biomet)FDA LinkGeneric 10/2011
1	Histamine (Histamine Dihydrochloride)FDA Link 10/2011
1	Peroxidase (Myeloperoxidase)IBA 04/2010
1	Polymeric Immunoglobulin Receptors (Polymeric Immunoglobulin Receptor)IBA 04/2010
1	Bisbenzimidazole (Hoechst 33258)IBA 08/2009
1	Pancreatic Elastase (Elastase)IBA 06/2009
1	Superoxides (Superoxide)IBA 06/2009
1	BuffersIBA 06/2009
1	NitrogenIBA 08/2003
1	Hydrochloric Acid (Hydrogen Chloride)FDA Link 08/2003
1	Oxygen (Dioxygen)IBA 08/2003
1	Carbon DioxideIBA 08/2003

Therapy/Procedure

8	Resuscitation 01/2022 - 10/2008
2	Therapeutics 01/2019 - 01/2017
1	Lab-On-A-Chip Devices 01/2019
1	Vagus Nerve Stimulation 10/2013
1	Critical Care (Surgical Intensive Care) 10/2004